River cruises offer a unique way to explore the world, combining luxurious accommodations with breathtaking scenery and immersive cultural experiences. Whether you’re seeking the lush Amazon, the ancient Nile, or the charm of European rivers, 2025 is packed with incredible itineraries. Dive into this guide to find your perfect river adventure.

1. Holland River Cruise with Kensington Tours

Imagine cruising through Holland in spring, surrounded by fields bursting with tulips and daffodils. This 11-night itinerary begins in Amsterdam, taking you through enchanting cities like Antwerp, Ghent, and Bruges. The highlight? A full day exploring Keukenhof, the world’s largest flower garden with over seven million blooms.

This tour is not just about flowers—it’s a culinary and cultural delight. From sampling Belgian waffles to admiring 16th-century cathedrals, every port offers something extraordinary. And with Kensington Tours’ luxury touches, you’ll feel pampered every step of the way.

Why Book This Cruise:

• Stroll through 70 acres of Keukenhof’s floral wonders.

• Indulge in Belgian treats like crepes and chocolates.

• Discover medieval gems in Antwerp and Bruges.

2. Rhine River Cruise to Switzerland with Riviera River Cruises

The Rhine River’s beauty is unmatched, and this journey to Switzerland showcases it at its finest. Riviera River Cruises offers an itinerary packed with unforgettable experiences, from sampling Alsace wines to meeting Swiss cheesemakers. This trip blends natural beauty with gourmet delights, making it a dream for food and wine enthusiasts.

Sail past charming German villages, scenic French vineyards, and Switzerland’s towering mountains. The personalized service on board ensures your every need is met, leaving you free to soak in the views and indulge in curated regional menus.

Highlights of the Trip:

• Taste authentic Swiss cheeses and Alsace wines.

• Explore medieval towns with cobbled streets and timbered houses.

• Marvel at the stunning Rhine Gorge, a UNESCO World Heritage Site.

3. Peru by River and Rail with Abercrombie & Kent

For adventurers seeking the exotic, this Peruvian itinerary combines river cruising with luxury rail travel. Begin your journey aboard the boutique Pure Amazon riverboat, navigating the lush Amazon Basin. Days are spent spotting rare wildlife, kayaking through rainforest waters, and fishing for piranhas.

The adventure doesn’t stop there—transfer to the Andean Explorer, South America’s only luxury sleeper train, for a breathtaking ride across the Andean Plateau. From the Peruvian Amazon to Lake Titicaca, this journey offers the best of both land and water exploration.

Must-Experience Moments:

• Spot sloths, howler monkeys, and vibrant birds in the Amazon.

• Relax in the opulent cabins of the Andean Explorer.

• Kayak through Lake Titicaca, the world’s highest navigable lake.

4. Mekong River Cruise with Aqua Expeditions

Experience the vibrant cultures of Cambodia and Vietnam on the Mekong River. Aqua Expeditions’ new ship, Aqua Mekong, offers luxurious suites with floor-to-ceiling windows, making the river your constant companion. Beyond the ship’s elegance, the itinerary is a cultural deep dive.

Explore floating villages, bustling markets, and artisan workshops. Activities like biking through rural landscapes and watching silk weavers at work bring you closer to local traditions. The ship also features a cinema, plunge pool, and a top-deck lounge for relaxation after a day of exploration.

Why You’ll Love It:

• Visit Phnom Penh’s royal palaces and historic sites.

• Kayak to floating villages and local markets.

• Enjoy five-star amenities on one of the Mekong’s most luxurious vessels.

5. Amazon River Voyage with Seabourn

The Amazon River is one of the world’s most mysterious and biodiverse destinations, and Seabourn delivers an experience that’s both luxurious and adventurous. Choose from a nine-day roundtrip from Manaus or a 21-day expedition ending in Rio de Janeiro.

As you glide through the lush waterways, you’ll encounter incredible wildlife, from howler monkeys to sloths and exotic birds. Expert guides onboard provide fascinating insights into the Amazon’s unique ecosystem, while excursions allow for up-close experiences.

Reasons to Go:

• Explore the Boca dos Botos, a pristine section of the Amazon.

• Spot rare wildlife with the help of expert naturalists.

• End your journey with the vibrant energy of Rio de Janeiro.

6. Colombia’s Magdalena River with AmaWaterways

Set sail on a journey that combines Colombia’s rich musical heritage with its stunning natural landscapes. AmaWaterways’ Magdalena River cruises, departing from Cartagena or Barranquilla, are the first of their kind from a major cruise line.

Onboard, you’ll enjoy top-tier amenities, including suites with balconies and a fitness center with spa treatments. Excursions include visits to historic towns, music-filled plazas, and vibrant markets, giving you a true taste of Colombia’s culture.

What to Expect:

• Dance to traditional Colombian rhythms in lively town squares.

• Cruise aboard a luxury vessel with spacious suites and gourmet dining.

• Explore Cartagena’s colonial charm and Barranquilla’s bustling energy.

7. Douro River Cruise in Portugal with Scenic

Portugal’s Douro River winds through rolling vineyards, medieval villages, and golden valleys, offering a feast for the senses. Scenic’s luxury river cruises elevate the experience with all-inclusive amenities, from onboard fine dining to private wine tastings at historic estates.

This seven-night journey begins in Porto, Portugal’s wine capital, and takes you deep into the Douro Valley, a UNESCO World Heritage Site. Along the way, you’ll visit quaint towns like Pinhão, sample the region’s famous port wine, and explore ancient monasteries. Scenic’s luxurious cabins and butler service ensure that every moment feels indulgent.

Why This Cruise is a Must:

• Tour historic wine estates and taste authentic port straight from the source.

• Visit the Baroque beauty of the Mateus Palace and gardens.

• Marvel at the Douro’s terraced vineyards and golden sunsets from your balcony.

8. Mississippi River Cruise with American Queen Voyages

For a taste of Southern charm and Americana, embark on a Mississippi River cruise. American Queen Voyages’ paddlewheel steamboats offer a nostalgic nod to history with all the modern luxuries you could want. Choose from itineraries that explore cities like New Orleans, Memphis, and St. Louis.

Highlights of this journey include live jazz performances, mouthwatering Southern cuisine, and visits to Civil War sites. The leisurely pace lets you soak in the cultural richness of the region, whether it’s sampling Creole delicacies in New Orleans or walking through Mark Twain’s boyhood home in Hannibal, Missouri.

Highlights of the Journey:

• Savor Southern specialties like gumbo, jambalaya, and pecan pie.

• Cruise on a traditional paddlewheel steamboat, complete with period décor.

• Explore New Orleans’ French Quarter and Graceland in Memphis.

9. Seine River Cruise with Uniworld

Paris may steal the show, but the Seine River offers so much more. Uniworld’s boutique river cruises take you from the heart of Paris to the Normandy coast, passing charming towns like Giverny, Rouen, and Honfleur along the way.

Immerse yourself in the romance of the French countryside as you visit Monet’s gardens, walk through medieval streets, and explore the D-Day landing beaches. Uniworld’s ship interiors are inspired by French elegance, featuring luxurious suites, farm-to-table cuisine, and fine wines.

Top Reasons to Sail the Seine:

• Visit Claude Monet’s house and gardens in Giverny.

• Explore the historic streets of Rouen, where Joan of Arc was tried.

• Dine on gourmet French cuisine paired with regional wines onboard.

10. Danube River Cruise with Viking

The Danube is a classic river cruise destination, flowing through Europe’s most storied cities and scenic landscapes. Viking’s Danube itineraries offer an immersive experience, visiting Budapest, Vienna, and Salzburg, among other highlights.

Each stop unveils rich history and culture, from exploring Vienna’s grand palaces to soaking in Budapest’s thermal baths. Onboard, Viking provides unmatched comfort, with panoramic staterooms and cultural enrichment programs. Whether you’re a history buff or a first-time cruiser, the Danube promises an unforgettable journey.

Unmissable Experiences:

• Take a guided tour of Schönbrunn Palace in Vienna.

• Relax in Budapest’s famous Gellért Baths.

• Wander the cobbled streets of Salzburg, Mozart’s birthplace.

11. Nile River Cruise with Sanctuary Retreats

The Nile River is a voyage through time, tracing the footsteps of ancient pharaohs and uncovering Egypt’s timeless wonders. Sanctuary Retreats’ boutique ships offer intimate experiences as you sail between Luxor and Aswan.

Highlights include guided tours of the Valley of the Kings, the Karnak Temple complex, and the Temple of Abu Simbel. Onboard, enjoy five-star amenities like plunge pools and gourmet Egyptian cuisine. Sanctuary Retreats focuses on eco-friendly travel, ensuring your journey leaves a light footprint.

What Makes This Cruise Special:

• Explore the tombs of ancient Egyptian royalty in the Valley of the Kings.

• Witness the grandeur of the Temple of Abu Simbel, carved into cliffs.

• Relax on a luxurious sun deck with Nile views as far as the eye can see.

12. Rhône River Cruise with Avalon Waterways

Sailing through southern France, the Rhône River takes you to Provence’s lavender fields, historic cities, and gourmet delights. Avalon Waterways combines modern luxury with personalized service, creating a cruise experience that feels both elegant and intimate.

Stops include Arles, known for its Roman amphitheater and Van Gogh inspirations, and Lyon, the gastronomic capital of France. Enjoy excursions to local vineyards, olive groves, and artisanal markets that immerse you in Provençal culture.

Why Choose a Rhône Cruise:

• Stroll through Provence’s lavender fields and picturesque villages.

• Visit Arles’ Roman amphitheater and Van Gogh Museum.

• Indulge in Lyon’s world-famous cuisine and wine pairings.

13. Chobe River Safari Cruise in Africa with AmaWaterways

For an unparalleled wildlife adventure, the Chobe River safari cruise in Botswana is a once-in-a-lifetime experience. AmaWaterways combines river cruising with luxury safari lodges, creating a seamless blend of comfort and exploration.

Sail through the Chobe National Park, home to one of the world’s largest concentrations of elephants. Spot lions, hippos, and crocodiles from the comfort of your ship or on guided safari drives. This itinerary also includes a visit to Victoria Falls, one of the Seven Natural Wonders of the World.

Key Experiences on the Chobe River:

• Witness herds of elephants bathing along the riverbanks.

• Take a guided safari drive to see Africa’s Big Five.

• Marvel at the thundering majesty of Victoria Falls.

Final Thoughts

River cruises in 2025 promise unmatched experiences, blending luxury, adventure, and cultural immersion. Whether you’re exploring Europe’s timeless rivers, the wild Amazon, or Africa’s Chobe, these journeys offer a fresh perspective on the world. So pack your bags, prepare for stunning views, and embark on a voyage you’ll never forget.